规格：50µL/100µL
货号：PN0064
价格：1350-50 µL， 2200元/100 µL
全名 | Anti-LC3B Rabbit pAb |
别名 | LC3, LC3B, MAP1A/1BLC3, MAP1A/MAP1B LC3 B, MAP1A/MAP1B light chain 3 B, MAP1ALC3, MAP1LC3B |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human,mouse，Rat (predicted: ,Goat, Chicken, Sheep, Monkey, Rabbit, Zebrafish, Pig) |
产品应用 | WB=1:1000-5000, IHC-P=1:50-500, IHC-F=1:50-500, IF=1:250-1000, Flow-Cyt=0.50 ug per 10^6 cells in a 100 µl suspension |
理论分子量 | 15kDa |
细胞定位 | 细胞核 细胞浆 |
性 状 | Liquid |
浓 度 | 500ug/ml |
免 疫 原 | KLH conjugated Synthetic peptide corresponding to Mouse LC3B |
亚 型 | IgG |
纯化方法 | Affinity purification |
UniProt ID | |
缓 冲 液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
保存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
Map1LC3, also known as LC3, is the human homolog of yeast Atg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. Three human Map1LC3 isoforms, MAP1LC3A, MAP1LC3B, and MAP1LC3C, undergo post-translational modifications during autophagy. And they differ in their post-translation modifications during autophagy. Map1LC3 also exists in two modified forms, an 18 kDa cytoplasmic form that was originally identified as a subunit of the microtubµLe-associated protein 1, and a 14-16 kDa form that is associated with the autophagosome membrane. This antibody can cross react with MAP1LC3A, MAP1LC3B, and MAP1LC3C.
