规格：50µL/100µL
货号：PN0063
价格：1350元/50 µL , 2200元/100 µL
全称 | Akt Antibody |
别名 | PKB;RAC;PRKBA;PKB-ALPHA;RAC-ALPHA; AKT1 ; AKT2; AKT3; Akt1/2/3; pan Akt; |
抗体来源 | Rabbit Monoclonal |
交叉反应 | Human;Mouse;Rat |
产品应用 | WB 1:1000-1:2000 IHC 1:100-1:200 ICC/IF 1:50-1:200 IHF 1:50-1:200 IP 1:20-1:50 FC 1:20-1:100 |
理论分子量 | 56kDa |
细胞定位 | 细胞膜，细胞质，细胞核 |
性 状 | Liquid |
浓 度 | |
免 疫 原 | A synthesized peptide derived from human AKT1 |
亚 型 | IgG |
纯化方法 | Affinity-chromatography |
UniProt ID | |
缓 冲 液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
保存条件 | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1.
